NSF International publishes toxicological oral risk assessment documents. These documents have been developed to allow toxicological evaluation of these chemicals as unregulated contaminants in drinking water. These documents consider both non-cancer and cancer endpoints and use risk assessment methodology developed by the U.S. Environmental Protection Agency (U.S. EPA).
The risk assessment documents were reviewed by the NSF Health Advisory Board (HAB). The HAB is comprised of renowned toxicologists from the regulatory community, academia and industry. Each document identifies key studies and critical toxicological effects for the chemical, selects appropriate uncertainty factors, and calculates an oral reference dose (RfD) following U.S. EPA guidelines. The total allowable concentration (TAC) and single product allowable concentration (SPAC) are calculated from the oral RfD using guidance provided in NSF/ANSI 60: Drinking water treatment chemicals - Health effects and NSF/ANSI 61: Drinking water system components - Health effects.
If you are interested in ordering risk assessment documents, please visit the NSF Bookstore.