Government and Professional Sector Support

  • Overview
  • Chemical Risk Assessments
  • Quantitative Microbial Risk Assessment (QMRA)
  • Chemical Evaluation to California Proposition 65
  • FIFRA Registration
  • Grant Collaborations

NSF International’s Applied Research Center provides government and professional sector regulatory support for manufacturers seeking to meet U.S. federal demands such as the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) or state mandates such as California Proposition 65.

Leveraging our technical analytical capabilities, we collaborate with academia, governments, the Department of Defense, innovators and others by developing new technologies, investigating emerging contaminants and applying scientific tools such as quantitative microbial risk assessment.

Chemical Risk Assessments

We provide two types of chemical risk assessments: human health risk assessment and quantitative structure-activity relationship (QSAR) modeling.

Human Health Risk Assessment

Human health risk assessments enable more efficient risk management decisions and more effective risk communication.

We provide a wide variety of risk assessment capabilities. We can:

  • Identify and evaluate relevant scientific literature
  • Document data gaps and make recommendations for resolution
  • Characterize risk with quantitative dose- and exposure-response modeling
  • Derive acceptable chemical-specific and/or chemical class-specific exposures
  • Publish results in peer-reviewed scientific journals

Quantitative Structure-Activity Relationship (QSAR) Modeling

A QSAR is a predictive model for chemical effects. We determine a mathematical relationship between a biological activity of a molecular system and its geometric and chemical characteristics to predict (either qualitatively or quantitatively) the physico-chemical, toxicological and environmental fate properties of chemicals.

QSAR modeling provides an alternative to animal testing. We can assess specific endpoints of toxicology concern without the necessity of additional in vitro or animal testing.

Quantitative Microbial Risk Assessment (QMRA)

Quantitative microbial risk assessment (QMRA) applies the principles of risk assessment to characterize the risk of infection/disease resulting from an exposure to microbial agents.

We can use QMRA to:

  • Address health questions for many areas of public health and safety, including recreational water, algae blooms, water re-use application and contamination in food
  • Document data gaps and make recommendations for resolution
  • Characterize risk with quantitative dose and exposure-response modeling to derive acceptable specific exposures

Chemical Evaluation to California Proposition 65

Proposition 65 is a “right to know” law that applies only to exposures to listed chemicals that are known to the State of California to cause cancer, birth defects or other reproductive harm.

We offer full Proposition 65 services, from analytical capabilities to generating the required data to full dossier assembly.

We may be able to leverage client data (such as product types and product formulations, which are useful for exposure calculation) from testing already completed in support of NSF certification or registration.

FIFRA Registration

The Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) is a United States law that regulates pesticide use and application to protect consumers and the environment.

We offer full FIFRA registration services, from laboratory capabilities to generate the required data to dossier assembly.

We may be able to leverage client data (such as product formulations) from testing already completed in support of NSF certification or registration.

Grant Collaborations

We contribute to the advancement of public health through collaborative projects with national and international utilities, governments, academia and innovators.

We can respond to grants as the sole or principal investigator or in collaboration with other groups.

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