NSF/ANSI 455-2: Dietary Supplements

NSF is transitioning clients from its current GMP registration (NSF/ANSI 173 Section 8) to NSF/ANSI 455 GMP certification to be able to certify facilities to a consensus-based national standard, and to allow manufacturers to reduce their annual audit burden.

We are currently accepting applications for audits for dietary supplements (NSF /ANSI 455-2), and the current dietary supplement GMP registration will be phased out entirely by 2022.

The updates to the NSF/ANSI 173 GMP registration for dietary supplements audits implemented in 2019 were the first step toward this new standard, and incorporated many of the audit requirements of NSF/ANSI 455-2. For manufacturers, the key differences between GMP registration and the NSF/ANSI 455 GMP certification are:

• The leading GMP audits for dietary supplements, cosmetics and OTC drugs based on current Good Manufacturing Practices and current federal regulations for each scope
• A defined audit process that determines audit duration, timeline for CAR reviews and ongoing monitoring requirements
• A grading system based on the number and severity of non-conformances
• Best industry practices based on retailer requirements
• Certification recognized by the Global Retailer and Manufacturer Alliance (GRMA) made up of leading retailers, manufacturers and other stakeholders

Transition smoothly from NSF/ANSI 173 GMP registration to NSF/ANSI 455-2.

To help you understand this new international standard for Good Manufacturing Practices (GMPs), NSF has developed resources to simplify your migration process.

If you are a current NSF client, please check the Announcements section of your NSF Connect portal for additional tools.

Roadmap to Certification: We’ve down each section of the standard to make the move to NSF/ANSI 455-2 more straightforward and provide background information about the standard.

FAQ: Our team of experts have answered a list of frequently asked questions (FAQs) for your convenience.

NSF/ANSI 455 Process Overview: Offers a clear overview of the process in becoming NSF/ANSI 455-2 certified.

Transition Guide: Contains a full overview of NSF/ANSI 455-2 GMP certification, a comparison chart of the new standard vs. GMP registration, a transition timeline and a detailed comparison table of audit templates.

Information Guide: Contains facts about NSF/ANSI 455-2, key changes from NSF/ANSI173 GMP registration and information about how to prepare for the new standard.

Please check back periodically for additional tools to help you throughout the migration process.