FAQ: NSF/ANSI/CAN 600 in Relation to Standards NSF/ANSI/CAN 60 and 61

Full Names of the Standards
NSF/ANSI/CAN 60: Drinking Water Treatment Chemicals - Health Effects
NSF/ANSI/CAN 61: Drinking Water System Components - Health Effects
NSF/ANSI/CAN 600: Health Effects Evaluation and Criteria for Chemicals in Drinking Water
Q: Does NSF/ANSI/CAN 600 Replace NSF/ANSI/CAN 60 and NSF/ANSI/CAN 61?
A: No, NSF/ANSI/CAN 600 is a companion standard to the flagship North American standards NSF/ANSI/CAN 60 and NSF/ANSI/CAN 61.
Q: What Do NSF/ANSI/CAN 60 and NSF/ANSI/CAN 61 Address?
A: NSF/ANSI/CAN 60 covers the health effects of drinking water treatment chemicals.
NSF/ANSI/CAN 61 covers the health effects of drinking water system components.
Q: What Is the Purpose of NSF/ANSI/CAN 600? Why Was It Created?
A: This standard defines the toxicology review procedures for evaluating the potential human health risk of contaminants that may be imparted to drinking water with anticipated use of treatment chemicals (NSF/ANSI/CAN 60) and water distribution system components (NSF/ANSI/CAN 61).
Until 2018, the content now comprising Standard 600 was located in Annexes A, C and D between NSF/ANSI/CAN Standards 60 and 61. Annex A in both standards contained the toxicological risk assessment procedures for establishing pass/fail criteria. On the other hand, Annex C (from NSF/ANSI/CAN 60) and Annex D (from NSF/ANSI/CAN 61) contained the pass/fail criteria.
The joint committees that oversee NSF/ANSI/CAN 60 and NSF/ANSI/CAN 61 decided to separate these sections into their own standard that would serve as a reference standard for all drinking water standards.
This consolidation was intended to make the toxicology data more accessible, as well as to make it easier to update and navigate the pass/fail criteria. This new reference standard was then designated NSF/ANSI/CAN 600.
Q: Is NSF/ANSI/CAN 600 a Standard To Be Certified Against?
A: No, it serves as a reference standard.
Q: Is There a Charge for NSF/ANSI/CAN 600?
A: Yes. However, anyone purchasing a copy of NSF/ANSI/CAN 60 or 61 will receive a complimentary copy of NSF/ANSI/CAN 600.
Q: Where Can I Learn More About These Three Standards?
A: Visit the following pages:
NSF/ANSI/CAN 60
- Free 2016 edition of NSF/ANSI 60
- The most recent edition of NSF/ANSI/CAN 60 (for purchase if not an NSF client)
NSF/ANSI/CAN 61
- Free 2016 edition of NSF/ANSI 61
- The most recent edition of NSF/ANSI/CAN 61 (for purchase if not an NSF client)
NSF/ANSI/CAN 600
- The most recent edition of NSF/ANSI/CAN 600 (for purchase if not an NSF client)
- Article: NSF/ANSI/CAN 600 Overview and Updated Health Effects Criteria
Overview of NSF/ANSI/CAN 600 and Updated Health Effects Criteria
How NSF Can Help You

What’s New with NSF

iNADO Partners with NSF to Support Members and Athletes
May 27, 2026iNADO is pleased to welcome NSF’s expertise and experience in support of its members and the athletes they serve
NSF Ends UK’s Three-Year Testing Gap with REG 31 Testing Designation
May 20, 2026NSF’s Oakdale laboratory becomes the UK’s sole facility offering comprehensive BS 6920 and REG 31 testing, closing a critical drinking water safety gap.
Tangent® Materials Announces Industry First: Tangent PolySheet™ CB Earns Certification to NSF 537, Becoming the First PFAS-Free NSF Standard 51 Food Equipment Material
May 20, 2026New food-grade synthetic cutting-board sheet, engineered from the ground up without per- and polyfluoroalkyl substances (PFAS), establishes a new materialsafety benchmark for food-contact and food-equipment applications.
NSF Annual Review and Impact Report 2025 Now Live
April 20, 2026NSF has published its Annual Review and Impact Report 2025, detailing the organization’s progress over the past year and outlining strategic priorities for 2026.
