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NSF/ANSI 455-2: Dietary Supplements GMP Certification

NSF offers audits and certification for dietary supplement products under the NSF/ANSI 455-2 Good Manufacturing Practices (GMP) standard.

NSF facilitated the NSF/ANSI 455-2 GMP audit standard with industry representatives, public health officials, regulators and consumer interest groups to promote safer dietary supplement products for consumers worldwide.

The standard is designed to strengthen safety, quality and trust throughout the supply chain and encompass regulatory requirements, retailer quality requirements, as well as industry best practices. Certification to the standard serves as a communication tool between manufacturers, regulators, retailers, and consumers.

Once certified, brands will receive an NSF certificate with the globally accepted ANSI logo, use the NSF/ANSI 455 GMP certification mark according to policy and appear on the NSF Product and Services Listings for Dietary Supplement GMPs . Certified clients will also have access to a dedicated 455 GMP certification co-marketing portal that contains certification marks and assets to help promote their certification.

The benefits of NSF/ANSI 455-2 GMP certification include:

  • Increases protection of your brand and minimizes risks
  • Prepares your facility for regulatory inspections
  • Helps your facility to build a strong quality and GMP program
  • Reduces the number of GMP audits and the financial costs associated with audits
  • Helps in fostering a culture of product safety and quality within your organization
  • Demonstrates your commitment to product safety and quality to your customers

Scope of certification

Facilities involved in the manufacturing, packaging, and/or warehouse & distribution of dietary supplements are in scope for NSF/ANSI 455-2 and may apply for certification.

Other resources

NSF Webinar: Dietary Supplement Storage Temperature Issues

Product and ingredient certification

Companies with GMP certification or registration receive instant eligibility to enter their products into NSF’s product certification program (NSF 527 and NSF Certified for Sport®). These benefits extend to contract manufacturers. When your contract manufacturer is GMP compliant, you reduce the time and cost of NSF testing and product certification.
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