Biosafety Cabinetry Testing and Certification Program
NSF tests to NSF/ANSI 49, which includes basic requirements for biosafety cabinet design, construction, and performance to provide reliable operation, durability, and cleanability.

NSF tests to NSF/ANSI 49, which includes basic requirements for biosafety cabinet design, construction, and performance to provide reliable operation, durability, and cleanability.
Noise level, illumination control, vibration control, and electrical safety are also included. The standard comprises detailed test procedures and informational annexes, including recommendations for installation, field certification, decontamination procedures, and decommissioning. NSF’s official biosafety cabinetry certification listings receive over 10,000 views per year.
Who can certification help?
- Cabinet users - Protects health and safety, prevents disease outbreaks and injuries.
- Manufacturers - Certifying your biosafety cabinet with NSF reduces risk and liability.
- Biosafety industry - NSF/ANSI 49 creates a benchmark to reference for quality and safety assurance.
- Biosafety officers - Using certified biosafety cabinets mitigates potential risks, protecting facility personnel from exposure and research projects from contamination.
- The public - Since biosafety cabinets are used in various clinical and research settings, their proper operation benefits nearly everyone.
How NSF Can Help You

What’s New with NSF

NSF Launches Independent Certification Standard for Compact Products
August 25, 2026New third-party certification verifies products cutting materials and shipping impacts while maintaining safety and performance.
CELSIUS® Products Earn NSF Certified for Sport® Certification
August 20, 2026CELSIUS® has earned NSF Certified for Sport® certification for select products, including the CELSIUS VIBES line, reinforcing the brand’s commitment to quality, transparency and consumer trust.
Thomas Vyles Honored With 2026 Walter F. Snyder Environmental Health Award
August 19, 2026The award honors Walter F. Snyder, co-founder and first executive director of NSF, and pioneers whose work advances environmental and public health.
NSF Hosts First External Review Panel for ‘NSF/KWTC 555’ with Key Asian Water Authorities
August 3, 2026Joint standard development gains momentum to enhance confidence in Asia’s water industry and advance drinking water safety.