Biosafety Cabinetry Testing and Certification Program
NSF tests to NSF/ANSI 49, which includes basic requirements for biosafety cabinet design, construction, and performance to provide reliable operation, durability, and cleanability.

NSF tests to NSF/ANSI 49, which includes basic requirements for biosafety cabinet design, construction, and performance to provide reliable operation, durability, and cleanability.
Noise level, illumination control, vibration control, and electrical safety are also included. The standard comprises detailed test procedures and informational annexes, including recommendations for installation, field certification, decontamination procedures, and decommissioning. NSF’s official biosafety cabinetry certification listings receive over 10,000 views per year.
Who can certification help?
- Cabinet users - Protects health and safety, prevents disease outbreaks and injuries.
- Manufacturers - Certifying your biosafety cabinet with NSF reduces risk and liability.
- Biosafety industry - NSF/ANSI 49 creates a benchmark to reference for quality and safety assurance.
- Biosafety officers - Using certified biosafety cabinets mitigates potential risks, protecting facility personnel from exposure and research projects from contamination.
- The public - Since biosafety cabinets are used in various clinical and research settings, their proper operation benefits nearly everyone.
How NSF Can Help You

What’s New with NSF

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Tangent® Materials Announces Industry First: Tangent PolySheet™ CB Earns Certification to NSF 537, Becoming the First PFAS-Free NSF Standard 51 Food Equipment Material
May 20, 2026New food-grade synthetic cutting-board sheet, engineered from the ground up without per- and polyfluoroalkyl substances (PFAS), establishes a new materialsafety benchmark for food-contact and food-equipment applications.
NSF Expands Food Equipment Portfolio with Electrical Safety Testing and Certification
April 30, 2026Manufacturers now have a “one-stop-shop” for both sanitation and electrical safety certification, enabling market expansion and regulatory compliance.