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FDA's Roadmap for Guidance Documents 2026

Date
December 2, 2025
Category

US Regulations

Description

At the end of November, the FDA published a roadmap for planned guidance documents for the current fiscal year 2026. The FDA divides this roadmap into three lists: A-List documents to be published with priority in 2026, B-List guidance documents that the FDA intends to publish depending on resource availability, and the “Under Construction” list, which the FDA intends to further develop for later publication. These lists include topics such as:

  1. A-List:

  • Use of Real-World Evidence to Support Regulatory Decision-Making for Medical Devices

  • Predetermined Change Control Plans for Medical Devices

  1. B-List

  • Artificial Intelligence-Enabled Device Software Functions: Lifecycle Management Considerations and Marketing Submission Recommendations

  • Medical Devices with Indications Associated with Weight Loss – Premarket Considerations

  • Content of Human Factors Information in Medical Device Marketing Submissions

  1. Under Construction List

  • Best Practices for Selecting a Predicate Device to Support a Premarket Notification [510(k)] Submission

  • Evaluation of Thermal Effects of Medical Devices that Produce Tissue Heating and/or Cooling

  • General/Specific Intended Use

New guidance documents always mean new requirements for manufacturers and distributors, and we are of course here to support you with old and new regulatory challenges as always.

CDRH Proposed Guidances for Fiscal Year 2026 (FY2026) | FDA