GMP Regulatory Compliance

NSF International provides GMP registration and NSF/ANSI 455 certification for dietary supplements, personal care products and OTC drugs.
Woman using digital tablet at a warehouse - GMP Regulatory Compliance Testing Services

GMP Registration

NSF International independently registers manufacturers that meet GMP requirements. Registration services are available for manufacturers of dietary supplements, ingredients and raw materials, as well as distribution, warehousing and packaging companies that want to demonstrate a commitment to public health. NSF is committed to simplifying the auditing needs of every client, including retailers’ auditing needs through its GRMA certification program.

Increase your company’s credibility and integrity and boost confidence in the preparedness of your facility for FDA inspection. Companies registered for GMP receive instant eligibility for entering products into NSF's product certification program. These benefits extend to contract manufacturers registered for GMP through NSF, too. When your contract manufacturer is GMP compliant, you decrease the time and cost of NSF testing and product certification.

Our global network of auditors and technical staff is committed to helping your facility achieve GMP registration. Receive in-depth audit reports, thorough corrective action guidance and rapid responses to your questions.

NSF/ANSI 455 GMP Certification

With input from industry representatives, public health officials, regulators and consumer interest groups, NSF International facilitated the development of the NSF/ANSI 455 GMP audit standards over the past five years.. We are currently transitioning clients from our GMP registration program to the NSF/ANSI 455 GMP certification program. This transition allows NSF to certify facilities to a consensus-based national standard and helps manufacturers reduce their annual audit burden.

We are currently accepting applications for audits for dietary supplements (NSF/ANSI 455-2), cosmetics and personal care products (455-3) and over-the-counter (OTC) drugs (455-4). The current dietary supplement GMP registration will be phased out entirely by 2022.

Both registration and certification provide leading GMP audits for dietary supplements, cosmetics and OTC drugs based on current Good Manufacturing Practices and federal regulations for each scope. For manufacturers, the key features NSF/ANSI 455 GMP certification provides in addition to GMP registration are:

  • A defined audit process that determines audit duration, timeline for corrective action request (CAR) reviews and ongoing monitoring requirements
  • A grading system based on the number and severity of non-conformances
  • Best industry practices based on retailer requirements
  • Certification audits accredited by ANSI

Ready to Begin the Process?

Contact us with questions or to receive a quote.

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